The effect on the variant on RNA or protein purpose, dependant on experimental evidence from submitters.

This benefit is calculated by NCBI according to data from submitters. Read our procedures for calculating the assessment standing. The number of submissions which contribute to this assessment status is demonstrated in parentheses.

This date signifies the last time this VCV file was updated. The update could possibly be because of an update to one of the bundled submitted records (SCVs), or as a result of an update that ClinVar designed into the variant like incorporating HGVS expressions or even a rs variety.

The worldwide minimal allele frequency calculated because of the one thousand Genomes Job. The insignificant allele at this site is indicated in parentheses and should be distinct in the allele represented by this VCV history.

The condition for your classification, provided by the submitter for this submitted (SCV) history. This column also involves the affected position and allele origin of individuals observed with this variant.

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There isn't any citations for germline classification of this variant in ClinVar. If you are aware of of citations for this variation, please think about submitting that info to ClinVar.

The number of variants in ClinVar which might be contained within just this gene, by using a website link to view the listing of variants.

These citations are determined by LitVar using the rs variety, so They could incorporate citations for multiple variant at this site. You should evaluation the LitVar effects cautiously in your variant of interest. Document very last current Might 19, 2024 

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